Anticorps Recombinant de lapin anti-KIR3DL1/CD158E

KIR3DL1/CD158E Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

243022H8

N° de cat : 98389-1-PBS

Synonymes

KIR3DL1, CD158 antigen-like family member E, CD158E, CD158E1, HLA-BW4-specific inhibitory NK cell receptor

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Galerie de données de validation

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  FC experiment of human PBMCs using 98389-1-RR (same clone as 98389-1-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human KIR3DL1/CD158E Rabbit RecAb (98389-1-RR, Clone:243022H8), or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 488 Anti-Human NCAM1/CD56. Cells were not fixed. Lymphocyte were gated. This data was developed using the same antibody clone with 98389-1-PBS in a different storage buffer formulation.

• 

  FC experiment of human PBMCs using 98389-1-RR (same clone as 98389-1-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human KIR3DL1/CD158E Rabbit RecAb (98389-1-RR, Clone:243022H8)(red), or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9)(blue) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. Lymphocyte were gated. This data was developed using the same antibody clone with 98389-1-PBS in a different storage buffer formulation.

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Informations sur le produit

98389-1-PBS cible KIR3DL1/CD158E dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
• Masse moléculaire calculée: 49 kDa
• Numéro d’acquisition GenBank: NM_013289.4
• Symbole du gène: KIR3DL1
• Identification du gène (NCBI): 3811
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR3DL1 is a receptor on natural killer (NK) cells for HLA Bw4 allele. It inhibits the activity of NK cells thus preventing cell lysis. KIR3DL1 and KIR3DS1 are highly homologous.

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