Anticorps Recombinant de lapin anti-KIR3DL1/CD158E

KIR3DL1/CD158E Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

243022H8

N° de cat : 98389-1-RR

Synonymes

KIR3DL1, CD158 antigen-like family member E, CD158E, CD158E1, HLA-BW4-specific inhibitory NK cell receptor

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Galerie de données de validation

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  FC experiment of human PBMCs using 98389-1-RR

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human KIR3DL1/CD158E Rabbit RecAb (98389-1-RR, Clone:243022H8), or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 488 Anti-Human NCAM1/CD56. Cells were not fixed. Lymphocyte were gated.

• 

  FC experiment of human PBMCs using 98389-1-RR

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human KIR3DL1/CD158E Rabbit RecAb (98389-1-RR, Clone:243022H8)(red), or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9)(blue) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. Lymphocyte were gated.

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Applications testées

• Résultats positifs en cytométrie: CMSP humaines,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

98389-1-RR cible KIR3DL1/CD158E dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
• Masse moléculaire calculée: 49 kDa
• Numéro d’acquisition GenBank: NM_013289.4
• Symbole du gène: KIR3DL1
• Identification du gène (NCBI): 3811
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2 - 8°C. Stable for one year after shipment.

Informations générales

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR3DL1 is a receptor on natural killer (NK) cells for HLA Bw4 allele. It inhibits the activity of NK cells thus preventing cell lysis. KIR3DL1 and KIR3DS1 are highly homologous.

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