Anticorps Polyclonal de lapin anti-KLF2

• Phare
• Validé par KD/KO

KLF2 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 23384-1-PBS

Synonymes

Krueppel like factor 2, Krueppel-like factor 2, Kruppel like factor 2 (lung), LKLF, Lung krueppel like factor

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Galerie de données de validation

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  WB analysis using 23384-1-AP (same clone as 23384-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 23384-1-AP (KLF2 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 23384-1-PBS in a different storage buffer formulation.

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Informations sur le produit

23384-1-PBS cible KLF2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: KLF2 Protéine recombinante Ag20019
• Nom complet: Kruppel-like factor 2 (lung)
• Masse moléculaire calculée: 355 aa, 37 kDa
• Poids moléculaire observé: 37-40 kDa, 60 kDa
• Numéro d’acquisition GenBank: BC071983
• Symbole du gène: KLF2
• Identification du gène (NCBI): 10365
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purifié par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

KLF2 (Kruppel-like Factor 2) belongs to zinc finger transcription factors, and it is implicated in a variety of biochemical processes, including lung development, embryonic erythropoiesis, epithelial integrity, T-cell viability, and adipogenesis (PMID: 17904406). KLF2 was identified as a negative regulator of T cell activation and adipogenesis. KLF2 also acts as a novel regulator of endothelial proinflammatory activation, inhibiting the inflammatory cytokine-mediated induction of adhesion molecule expression and immune cell adhesion (PMID:15718498). KLF2-null mice exhibit abnormal blood vessel formation, resulting in embryonic haemorrhage and death (PMID: 32132543). KLF2 can be detected 60 kDa by post-translationally modified (PMID: 36466816).

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