Anticorps Recombinant de lapin anti-KLK3/PSA

KLK3/PSA Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241223E9

N° de cat : 84059-7-PBS

Synonymes

KLK3, Kallikrein-3, Kallikrein 3, Gamma-seminoprotein, EC:3.4.21.77

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Galerie de données de validation

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  WB analysis of LNCaP using 84059-7-RR (same clone as 84059-7-PBS)

  LNCaP cells were subjected to SDS PAGE followed by western blot with 84059-7-RR (KLK3/PSA antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84059-7-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 84059-7-RR

  Biolayer interferometry (BLl) kinetic assays of 84059-7-RR against Human KLK3/PSA were performed. The affinity constant is 0.307 nM.

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Informations sur le produit

84059-7-PBS cible KLK3/PSA dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: kallikrein-related peptidase 3
• Masse moléculaire calculée: 29 kDa
• Poids moléculaire observé: 30-34 kDa
• Numéro d’acquisition GenBank: NM_001648.2
• Symbole du gène: KLK3
• Identification du gène (NCBI): 354
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. kallikrein-related peptidase 3, which is also called PSA (prostate-specific antigen) in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. KLK3 has 5 isoforms produced by alternative splicing.

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