Anticorps Monoclonal anti-KLRG1

KLRG1 Monoclonal Antibody for FC

Hôte / Isotype

Golden Syrian Hamster / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

2F1

N° de cat : 65084-1-Ig

Synonymes

2F1 Ag, Klrg1, MAFA, MAFA L

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Galerie de données de validation

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  FC experiment of mouse splenocytes using 65084-1-Ig

  1X10^6 mouse splenocytes were surface stained with 0.5 ug Anti-Mouse KLRG1 (65084-1-Ig, Clone: 2F1) and FITC anti-Golden Syrian Hamster IgG Antibody at dilution 1:50 (green), or stained with 0.5 ug Golden Syrian Hamster IgG isotype control and FITC anti-Golden Syrian Hamster IgG Antibody at dilution 1:50 (black). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: splénocytes de souris,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

65084-1-Ig cible KLRG1 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Golden Syrian Hamster / IgG
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: s/o
• Nom complet: killer cell lectin-like receptor subfamily G, member 1
• Numéro d’acquisition GenBank: BC101953
• Symbole du gène: Klrg1
• Identification du gène (NCBI): 50928
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité
• Tampon de stockage: Tampon à base de phosphate avec azoture de sodium à 0,09 %, pH 7,2.
• Conditions de stockage: Stocker à une température comprise entre 2 °C et 8 °C.

Informations générales

KLRG1 (killer cell lectin-like receptor subfamily G, member 1) is a C-type lectin inhibitory receptor that contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic domain. KLRG1 is expressed by subsets of NK and T cells, existing both as a monomer and as a disulfide-linked homodimer (PMID: 10741410; 19604491). It is considered to be a cell differentiation marker for NK and T cells and is strongly induced by viral and other infections (PMID: 20373518). Through interactions with members of the cadherin family, KLRG1 plays an inhibitory role on NK- and T-cell function (PMID: 19009530; 20373518).