Anticorps Polyclonal de lapin anti-KNCN

KNCN Polyclonal Antibody for IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 21532-1-PBS

Synonymes

Kino, kinocilin

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Galerie de données de validation

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  IHC staining of mouse liver using 21532-1-AP (same clone as 21532-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 21532-1-AP (KNCN antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21532-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse liver using 21532-1-AP (same clone as 21532-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 21532-1-AP (KNCN antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21532-1-PBS in a different storage buffer formulation.

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Informations sur le produit

21532-1-PBS cible KNCN dans les applications de IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: KNCN Protéine recombinante Ag16160
• Nom complet: kinocilin
• Masse moléculaire calculée: 124 aa, 13 kDa
• Numéro d’acquisition GenBank: BC101295
• Symbole du gène: KNCN
• Identification du gène (NCBI): 148930
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Kinocilin (KNCN) was first detected in the kinocilia of vestibular and auditory hair cells at embryonic days 14.5 and 18.5, respectively. In mature auditory hair cells, KNCN was present at the cuticular plate, at the base of each stereocilium. KNCN was also expressed by the pillar cells and Deiters cells, both of which contain prominent transcellular and apical bundles of microtubules. KNCN expression was detected in both cochlear and vestibular hair cells. KNCN plays a role in stabilizing dense microtubular networks or invesicular trafficking (PMID: 30254566).

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