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Anticorps Polyclonal de lapin anti-KREMEN1

KREMEN1 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 25434-1-PBS

Synonymes

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using KREMEN1 Polyclonal antibody (25434-1-AP)

    WB analysis using 25434-1-AP (same clone as 25434-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 25434-1-AP (KREMEN1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25434-1-PBS in a different storage buffer formulation.

Informations sur le produit

25434-1-PBS cible KREMEN1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

Réactivité Humain, rat, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène KREMEN1 Protéine recombinante Ag22092
Nom complet kringle containing transmembrane protein 1
Masse moléculaire calculée 473 aa, 52 kDa
Poids moléculaire observé50 kDa
Numéro d’acquisition GenBankBC063787
Symbole du gène KREMEN1
Identification du gène (NCBI) 83999
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Kringle containing transmembrane protein 1 (KREMEN1, also known as KRM1, ECTD13, and KREMEN) is a transmembrane receptor located in the membrane. During the development of various organs, including the nervous system, limbs, and liver, KREMEN1 synergizes with the Dkk proteins to inhibit Wnt signaling (PMID: 18505822). KREMEN1 has been reported as a tumor suppressor, preventing cancer cell survival in a ligand-poor environment (PMID: 31069116). Variations and mutations of KREMEN1 have been associated with ectodermal dysplasia and Hand-foot-and-mouth disease (PMID: 34028942; 31911601).

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