Anticorps Polyclonal de lapin anti-Kindlin 2

Kindlin 2 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 29911-1-PBS

Synonymes

FERMT2, FERMT 2, mig 2, Kindlin-2, kindlin2

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Galerie de données de validation

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  WB analysis using 29911-1-AP (same clone as 29911-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 29911-1-AP (Kindlin 2 antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29911-1-PBS in a different storage buffer formulation.

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  IHC staining of human colon using 29911-1-AP (same clone as 29911-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human normal colon slide using 29911-1-AP (Kindlin 2 antibody) at dilution of 1:1200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29911-1-PBS in a different storage buffer formulation.

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  IHC staining of human colon using 29911-1-AP (same clone as 29911-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human normal colon slide using 29911-1-AP (Kindlin 2 antibody) at dilution of 1:1200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29911-1-PBS in a different storage buffer formulation.

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  IHC staining of human lung cancer using 29911-1-AP (same clone as 29911-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 29911-1-AP (Kindlin 2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29911-1-PBS in a different storage buffer formulation.

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Informations sur le produit

29911-1-PBS cible Kindlin 2 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Kindlin 2 Protéine recombinante Ag31795
• Nom complet: fermitin family homolog 2 (Drosophila)
• Masse moléculaire calculée: 680 aa, 78 kDa
• Poids moléculaire observé: 78 kDa
• Numéro d’acquisition GenBank: BC017327
• Symbole du gène: Kindlin 2
• Identification du gène (NCBI): 10979
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

FERMT2, also named as KIND2, MIG2, PLEKHC1, MIG-2 and Kindlin-2, belongs to the kindlin family. There are three FERMT2 isoforms that participate in the connection between extracellular matrix (ECM) adhesion sites and the actin cytoskeleton and also in the orchestration of actin assembly and cell shape modulation. FERMT2 recruits migfilin (FBLP1) protein to cell-ECM focal adhesion sites. Variable expression in human cancers and mesenchymal cancer invasion are now linked with FERMT2, which may plays important role in carcinormas development.

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