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Anticorps Polyclonal de lapin anti-L-Myc

L-Myc Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 14584-1-PBS

Synonymes

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using L-Myc Polyclonal antibody (14584-1-AP)

    WB analysis using 14584-1-AP (same clone as 14584-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 14584-1-AP (L-Myc antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14584-1-PBS in a different storage buffer formulation.

Informations sur le produit

14584-1-PBS cible L-Myc dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène L-Myc Protéine recombinante Ag6105
Nom complet v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)
Masse moléculaire calculée 40 kDa
Poids moléculaire observé68 kDa
Numéro d’acquisition GenBankBC011864
Symbole du gène MYCL1
Identification du gène (NCBI) 4610
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The MYC gene family consists of 3 members, C-MYC, L-MYC, and N-MYC, all of which belong to the superfamily of basic helix-loop-helix leucine zipper (bHLHLZ) DNA binding proteins. L-MYC encodes a nuclear phosphoprotein with 364 amino acids, heterodimerizing with partner protein Max and acts as a transcription factor to control the expression of target genes. L-Myc is involved in many biological processes, including cell proliferation, differentiation, apoptosis and has been found to be amplified and over-expressed in some malignancies. L-Myc amplification has been reported in small-cell lung cancer (PMID: 25528583, 33524794). The observed molecular weight of L-Myc is 68 kDa, which is consistent with the description in the literature (PMID: 8657155).

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