Anticorps Recombinant de lapin anti-L1CAM/CD171

L1CAM/CD171 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

250101F8

N° de cat : 98510-1-PBS

Synonymes

L1cam, N-CAM-L1, CAML1, CD171, N CAM L1

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Galerie de données de validation

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  FC experiment of Transfected HEK-293T using 98510-1-RR (same clone as 98510-1-PBS)

  1x10^6 293T cells or L1CAM/CD171 transfected 293T cells were surface stained with 0.25 ug Anti-Mouse L1CAM/CD171 Rabbit RecAb (98510-1-RR, Clone: 250101F8) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98510-1-PBS in a different storage buffer formulation.

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  FC experiment of Transfected HEK-293T using 98510-1-RR (same clone as 98510-1-PBS)

  1x10^6 293T cells or L1CAM/CD171 transfected 293T cells were surface stained with 0.25 ug Anti-Mouse L1CAM/CD171 Rabbit RecAb (98510-1-RR, Clone: 250101F8) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98510-1-PBS in a different storage buffer formulation.

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Informations sur le produit

98510-1-PBS cible L1CAM/CD171 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: L1CAM/CD171 Protéine recombinante Eg3022
• Nom complet: L1 cell adhesion molecule
• Masse moléculaire calculée: 141 kDa
• Numéro d’acquisition GenBank: N/A
• Symbole du gène: L1cam
• Identification du gène (NCBI): 16728
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

L1CAM, also known as NCAM-L1 or CD171, is a cell adhesion molecule of the immunoglobulin superfamily. It is a 200-220 kDa transmembrane glycoprotein composed of six Ig-like domains and five fibronectin type III repeats followed by a transmembrane region and a highly conserved cytoplasmic tail (PMID: 3412448; 22796939). L1CAM is primarily expressed in the nervous system and is involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, cerebellar granule cell migration, neurite outgrowth on Schwann cells and interactions among epithelial cells of intestinal crypts (PMID: 3412448; 10767310). L1CAM is overexpressed in many human cancers and is often associated with bad prognosis (PMID: 27267927; 26111503).

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