Anticorps Recombinant de lapin anti-L1CAM/CD171

L1CAM/CD171 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

250101F8

N° de cat : 98510-1-RR

Synonymes

L1cam, N-CAM-L1, CAML1, CD171, N CAM L1

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Galerie de données de validation

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  FC experiment of Transfected HEK-293T using 98510-1-RR

  1x10^6 293T cells or L1CAM/CD171 transfected 293T cells were surface stained with 0.25 ug Anti-Mouse L1CAM/CD171 Rabbit RecAb (98510-1-RR, Clone: 250101F8) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

• 

  FC experiment of Transfected HEK-293T using 98510-1-RR

  1x10^6 293T cells or L1CAM/CD171 transfected 293T cells were surface stained with 0.25 ug Anti-Mouse L1CAM/CD171 Rabbit RecAb (98510-1-RR, Clone: 250101F8) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: Transfected HEK-293T cells,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

98510-1-RR cible L1CAM/CD171 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: L1CAM/CD171 Protéine recombinante Eg3022
• Nom complet: L1 cell adhesion molecule
• Masse moléculaire calculée: 141 kDa
• Numéro d’acquisition GenBank: N/A
• Symbole du gène: L1cam
• Identification du gène (NCBI): 16728
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2 - 8°C. Stable for one year after shipment.

Informations générales

L1CAM, also known as NCAM-L1 or CD171, is a cell adhesion molecule of the immunoglobulin superfamily. It is a 200-220 kDa transmembrane glycoprotein composed of six Ig-like domains and five fibronectin type III repeats followed by a transmembrane region and a highly conserved cytoplasmic tail (PMID: 3412448; 22796939). L1CAM is primarily expressed in the nervous system and is involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, cerebellar granule cell migration, neurite outgrowth on Schwann cells and interactions among epithelial cells of intestinal crypts (PMID: 3412448; 10767310). L1CAM is overexpressed in many human cancers and is often associated with bad prognosis (PMID: 27267927; 26111503).

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