Anticorps Polyclonal de lapin anti-L3HYPDH

L3HYPDH Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 33146-1-PBS

Synonymes

C14orf149, EC:4.2.1.77, Trans-3-hydroxy-L-proline dehydratase, Trans-L-3-hydroxyproline dehydratase

---

Galerie de données de validation

• 

  WB analysis using 33146-1-AP (same clone as 33146-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 33146-1-AP (L3HYPDH antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 33146-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

33146-1-PBS cible L3HYPDH dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: L3HYPDH Protéine recombinante Ag37121
• Nom complet: chromosome 14 open reading frame 149
• Masse moléculaire calculée: 38 kDa
• Poids moléculaire observé: 40 kDa
• Numéro d’acquisition GenBank: BC012131
• Symbole du gène: C14orf149
• Identification du gène (NCBI): 112849
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Trans-3-hydroxy-L-proline dehydratase (L3HYPDH) is an enzyme that catalyzes the conversion of trans-3-hydroxy-L-proline to delta(1)-pyrroline-2-carboxylate. This enzyme is involved in the degradation of dietary proteins containing trans-3-hydroxy-L-proline, such as collagen IV. Additionally, L3HYPDH has been identified as an interferon-stimulated gene (ISG) with antiviral activity, particularly against viruses like EV71 (PMID: 35891782). It also plays a role in the genetic regulation of working memory and has been implicated in the mitochondrial pathway associated with autism spectrum disorder (PMID: 32490597).

{{ptg:RelatedPrimaryAntibodies}}