Anticorps Polyclonal de lapin anti-L3MBTL2

L3MBTL2 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 24435-1-PBS

Synonymes

L(3)mbt-like protein 2, L(3)mbt like protein 2, l(3)mbt like 2 (Drosophila), H-l(3)mbt-like protein 2, H l(3)mbt like protein 2

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Galerie de données de validation

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  WB analysis using 24435-1-AP (same clone as 24435-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 24435-1-AP (L3MBTL2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24435-1-PBS in a different storage buffer formulation.

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Informations sur le produit

24435-1-PBS cible L3MBTL2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: L3MBTL2 Protéine recombinante Ag19571
• Nom complet: l(3)mbt-like 2 (Drosophila)
• Masse moléculaire calculée: 705 aa, 79 kDa
• Poids moléculaire observé: 95-100 kDa
• Numéro d’acquisition GenBank: BC017191
• Symbole du gène: L3MBTL2
• Identification du gène (NCBI): 83746
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

L3MBTL2 (Lethal (3) malignant brain tumor like 2) is a member of the MBT-domain proteins, which are involved in transcriptional repression and implicated in chromatin compaction. L3MBTL2 was most highly expressed in pachytene spermatocytes within the testis (PMID: 30760872).In addition, mutations in L3MBTL2 are prevalent in various cancers including leukemia, a disease characterized by alterations in multiple DNA repair proteins (PMID: 29581593).

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