Anticorps Polyclonal de lapin anti-L3MBTL3

L3MBTL3 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 28112-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 28112-1-AP (same clone as 28112-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 28112-1-AP (L3MBTL3 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28112-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse cerebellum using 28112-1-AP (same clone as 28112-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 28112-1-AP (L3MBTL3 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28112-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse cerebellum using 28112-1-AP (same clone as 28112-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 28112-1-AP (L3MBTL3 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28112-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse cerebellum using 28112-1-AP (same clone as 28112-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 28112-1-AP (L3MBTL3 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28112-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse cerebellum using 28112-1-AP (same clone as 28112-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 28112-1-AP (L3MBTL3 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28112-1-PBS in a different storage buffer formulation.

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  IF Staining of U2OS using 28112-1-AP (same clone as 28112-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed U2OS cells using L3MBTL3 antibody (28112-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), CL594-Phalloidin (red). This data was developed using the same antibody clone with 28112-1-PBS in a different storage buffer formulation.

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Informations sur le produit

28112-1-PBS cible L3MBTL3 dans les applications de WB, IHC, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: L3MBTL3 Protéine recombinante Ag27136
• Nom complet: l(3)mbt-like 3 (Drosophila)
• Masse moléculaire calculée: 88 aa, 3 kDa
• Poids moléculaire observé: 88 kDa
• Numéro d’acquisition GenBank: BC060845
• Symbole du gène: L3MBTL3
• Identification du gène (NCBI): 84456
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

L3MBTL3, also named as MBT1 and KIAA1798, belongs to the Malignant brain tumor (MBT) family. L3MBTL3 can bind to methyl lysine in histone, further affecting the transcription and its abnormal regulation associated with many diseases (PMID: 34373992). Additionally, researches have shown that L3MBTL3 plays a role in meduloblastoma formation and normal hematopoiesis in humans (PMID: 26317848). L3MBTL3 has 2 isoforms with the molecular mass of 86 and 88 kDa.

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