Anticorps Polyclonal de lapin anti-LAMA4 (Isoform 3)

LAMA4 (Isoform 3) Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 10465-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis of human heart using 10465-1-AP (same clone as 10465-1-PBS)

  human heart tissue were subjected to SDS PAGE followed by western blot with 10465-1-AP (LAMA4 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10465-1-PBS in a different storage buffer formulation.

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  WB analysis of human skeletal muscle using 10465-1-AP (same clone as 10465-1-PBS)

  human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 10465-1-AP (LAMA4 antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10465-1-PBS in a different storage buffer formulation.

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  IHC staining of human ovary using 10465-1-AP (same clone as 10465-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary using 10465-1-AP (LAMA4 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 10465-1-PBS in a different storage buffer formulation.

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  IHC staining of human ovary using 10465-1-AP (same clone as 10465-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary using 10465-1-AP (LAMA4 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 10465-1-PBS in a different storage buffer formulation.

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Informations sur le produit

10465-1-PBS cible LAMA4 (Isoform 3) dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: LAMA4 (Isoform 3) Protéine recombinante Ag0736
• Nom complet: laminin, alpha 4
• Masse moléculaire calculée: 13 kDa
• Poids moléculaire observé: 11-13 kDa
• Numéro d’acquisition GenBank: BC004241
• Symbole du gène: Laminin alpha 4/LAMA4
• Identification du gène (NCBI): 3910
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Laminin is a basement membrane glycoprotein composed of three nonidentical chains, A, B1, and B2 (PMID: 7959779). LAMA4 (laminin, alpha 4), an A chain variant, is a subunit of laminin-8 (laminin-411), laminin-9 (laminin-421) and laminin-14 (laminin-423) (PMID: 10842354; 10964957). LAMA4 is widely distributed in developing and adult human tissues, and mainly localized to mesenchyme-derived tissues (PMID: 12133914). It may have a role in formation and function of endothelium, transmigration of inflammatory cells through endothelium, and invasion of certain tumors (PMID: 17533363). Three alternatively spliced mRNAs give rise to three isoforms. This antibody was generated against the full length (1-120aa) of isoform 3.

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