Anticorps Polyclonal de lapin anti-LARP7

• Phare
• Validé par KD/KO

LARP7 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 17067-1-PBS

Synonymes

HDCMA18P, hLARP7, La related protein 7, La-related protein 7, PIP7S

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Galerie de données de validation

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  WB analysis using 17067-1-AP (same clone as 17067-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 17067-1-AP (LARP7 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17067-1-PBS in a different storage buffer formulation.

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  WB analysis of human brain using 17067-1-AP (same clone as 17067-1-PBS)

  human brain tissue were subjected to SDS PAGE followed by western blot with 17067-1-AP (LARP7 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17067-1-PBS in a different storage buffer formulation.

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  IHC staining of human breast cancer using 17067-1-AP (same clone as 17067-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 17067-1-AP (LARP7 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17067-1-PBS in a different storage buffer formulation.

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  IHC staining of human stomach cancer using 17067-1-AP (same clone as 17067-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue slide using 17067-1-AP (LARP7 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17067-1-PBS in a different storage buffer formulation.

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  IHC staining of human stomach cancer using 17067-1-AP (same clone as 17067-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue slide using 17067-1-AP (LARP7 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17067-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver using 17067-1-AP (same clone as 17067-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver using 17067-1-AP (LARP7 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 17067-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver using 17067-1-AP (same clone as 17067-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver using 17067-1-AP (LARP7 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 17067-1-PBS in a different storage buffer formulation.

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  IHC staining of human spleen using 17067-1-AP (same clone as 17067-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human spleen using 17067-1-AP (LARP7 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 17067-1-PBS in a different storage buffer formulation.

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  IHC staining of human spleen using 17067-1-AP (same clone as 17067-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human spleen using 17067-1-AP (LARP7 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 17067-1-PBS in a different storage buffer formulation.

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  IHC staining of human ovary using 17067-1-AP (same clone as 17067-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary using 17067-1-AP (LARP7 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 17067-1-PBS in a different storage buffer formulation.

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  IHC staining of human ovary using 17067-1-AP (same clone as 17067-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary using 17067-1-AP (LARP7 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 17067-1-PBS in a different storage buffer formulation.

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  IHC staining of human placenta using 17067-1-AP (same clone as 17067-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta using 17067-1-AP (LARP7 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 17067-1-PBS in a different storage buffer formulation.

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  IHC staining of human placenta using 17067-1-AP (same clone as 17067-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta using 17067-1-AP (LARP7 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 17067-1-PBS in a different storage buffer formulation.

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  IHC staining of human testis using 17067-1-AP (same clone as 17067-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human testis using 17067-1-AP (LARP7 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 17067-1-PBS in a different storage buffer formulation.

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  IHC staining of human testis using 17067-1-AP (same clone as 17067-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human testis using 17067-1-AP (LARP7 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 17067-1-PBS in a different storage buffer formulation.

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  IHC staining of human skin using 17067-1-AP (same clone as 17067-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skin using 17067-1-AP (LARP7 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 17067-1-PBS in a different storage buffer formulation.

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  IHC staining of human skin using 17067-1-AP (same clone as 17067-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skin using 17067-1-AP (LARP7 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 17067-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 17067-1-AP (same clone as 17067-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 17067-1-AP (LARP7 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17067-1-PBS in a different storage buffer formulation.

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  IF Staining of HeLa using 17067-1-AP (same clone as 17067-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed HeLa cells using LARP7 antibody (17067-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 17067-1-PBS in a different storage buffer formulation.

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Informations sur le produit

17067-1-PBS cible LARP7 dans les applications de WB, IHC, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: LARP7 Protéine recombinante Ag10891
• Nom complet: La ribonucleoprotein domain family, member 7
• Masse moléculaire calculée: 582 aa, 67 kDa
• Poids moléculaire observé: 67 kDa
• Numéro d’acquisition GenBank: BC006981
• Symbole du gène: LARP7
• Identification du gène (NCBI): 51574
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

LARP7 belongs to the LARP RNA-binding protein family, which includes the lupus LA antigen gene, and modulates the metabolism and function of a variety of RNA species [PMID:20138158]. LARP7 binds to the 7SK RNP complex, and sequesters the positive transcription elongation factor b (P-TEFb) in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. binds to and stabilizes 7sk snRNA[PMID:19416841].

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