Anticorps Monoclonal anti-LBP

LBP Monoclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Mouse / IgG2b

Réactivité testée

Humain

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

3A7E3

N° de cat : 66181-1-PBS

Synonymes

LBP

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Galerie de données de validation

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  WB analysis of Jurkat using 66181-1-Ig (same clone as 66181-1-PBS)

  Jurkat cells were subjected to SDS PAGE followed by western blot with 66181-1-Ig (LBP Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66181-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver using 66181-1-Ig (same clone as 66181-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 66181-1-Ig (LBP antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66181-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver using 66181-1-Ig (same clone as 66181-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 66181-1-Ig (LBP antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66181-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver cancer using 66181-1-Ig (same clone as 66181-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 66181-1-Ig (LBP antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66181-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver cancer using 66181-1-Ig (same clone as 66181-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 66181-1-Ig (LBP antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66181-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human kidney using 66181-1-Ig (same clone as 66181-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 66181-1-Ig (LBP antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66181-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human kidney using 66181-1-Ig (same clone as 66181-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 66181-1-Ig (LBP antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66181-1-PBS in a different storage buffer formulation.

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Informations sur le produit

66181-1-PBS cible LBP dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG2b
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: LBP Protéine recombinante Ag13485
• Nom complet: lipopolysaccharide binding protein
• Masse moléculaire calculée: 481 aa, 53 kDa
• Poids moléculaire observé: 60 kDa
• Numéro d’acquisition GenBank: BC022256
• Symbole du gène: LBP
• Identification du gène (NCBI): 3929
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

LBP (lipopolysaccharide-binding protein) is an acute-phase protein, predominantly synthesized by hepatocytes. It is present in normal serum at concentrations of 5 to 10 μg/ml, rising up to 200 μg/ml 24 h after induction of an acute-phase response. LBP binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria, and acts as an affinity enhancer for CD14, facilitating its association with LPS. (PMID: 9665271; 11598069)

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