Anticorps Polyclonal de lapin anti-LGALS13

LGALS13 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 17823-1-PBS

Synonymes

Galectin-13, Gal 13, GAL13, Gal-13, Galactoside-binding soluble lectin 13

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Galerie de données de validation

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  WB analysis using 17823-1-AP (same clone as 17823-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 17823-1-AP (LGALS13 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17823-1-PBS in a different storage buffer formulation.

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  IHC staining of human placenta using 17823-1-AP (same clone as 17823-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 17823-1-AP (LGALS13 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17823-1-PBS in a different storage buffer formulation.

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Informations sur le produit

17823-1-PBS cible LGALS13 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: LGALS13 Protéine recombinante Ag12192
• Nom complet: lectin, galactoside-binding, soluble, 13
• Masse moléculaire calculée: 139 aa, 16 kDa
• Poids moléculaire observé: 16 kDa
• Numéro d’acquisition GenBank: BC066304
• Symbole du gène: LGALS13
• Identification du gène (NCBI): 29124
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Galectins are glycan-binding proteins that regulate innate and adaptive immune responses, and some confer maternal-fetal immune tolerance in eutherian mammals.  Three of the five human cluster galectins are solely expressed in the placenta, where they may confer additional immunoregulatory functions to enable deep placentation (PMID: 25191322). One of these is galactoside-binding soluble lectin 13 (LGALS13, also known as Galectin-13 and PP13), which has a high affinity for the sugar residues of glycoproteins. PP13 is implicated in placentation and is involved in inflammation and immune defense required for trophoblast invasion during uterine artery remodeling in early pregnancy (PMID: 19497882; 10527825; 21596368; 26018511).

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