Anticorps Polyclonal de lapin anti-LGALS3BP

LGALS3BP Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 23307-1-PBS

Synonymes

90K, BTBD17B, Galectin 3 binding protein, Galectin-3-binding protein, Lectin galactoside-binding soluble 3-binding protein

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Galerie de données de validation

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  WB analysis of HepG2 using 23307-1-AP (same clone as 23307-1-PBS)

  HepG2 cells were subjected to SDS PAGE followed by western blot with 23307-1-AP (LGALS3BP antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 23307-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse brain using 23307-1-AP (same clone as 23307-1-PBS)

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 23307-1-AP (LGALS3BP antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 23307-1-PBS in a different storage buffer formulation.

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  IHC staining of human breast cancer using 23307-1-AP (same clone as 23307-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer slide using 23307-1-AP (LGALS3BP Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 23307-1-PBS in a different storage buffer formulation.

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  IHC staining of human breast cancer using 23307-1-AP (same clone as 23307-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer slide using 23307-1-AP (LGALS3BP Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 23307-1-PBS in a different storage buffer formulation.

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  IHC staining of human skin using 23307-1-AP (same clone as 23307-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skin slide using 23307-1-AP (LGALS3BP Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 23307-1-PBS in a different storage buffer formulation.

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  IF Staining of A431 using 23307-1-AP (same clone as 23307-1-PBS)

  Immunofluorescent analysis of (-20°C Methanol) fixed A431 cells using LGALS3BP antibody (23307-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 23307-1-PBS in a different storage buffer formulation.

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  IF Staining of HepG2 using 23307-1-AP (same clone as 23307-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using LGALS3BP antibody (23307-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 23307-1-PBS in a different storage buffer formulation.

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Informations sur le produit

23307-1-PBS cible LGALS3BP dans les applications de WB, IHC, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: LGALS3BP Protéine recombinante Ag19700
• Nom complet: lectin, galactoside-binding, soluble, 3 binding protein
• Masse moléculaire calculée: 585 aa, 65 kDa
• Poids moléculaire observé: 65-70 kDa
• Numéro d’acquisition GenBank: BC002403
• Symbole du gène: LGALS3BP
• Identification du gène (NCBI): 3959
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin-3-binding protein (LGALS3BP, also known as 90K or Mac-2 BP) is a secreted glycoprotein which binds galectin-3, galectin-1, beta1 integrins, collagens and fibronectin (PMID: 8034587; 8024581; 11146440; 9501082). It has been implicated in tumor metastatic processes, as well as in other cell adhesion and immune functions. Levels of LGALS3BP have been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV) (PMID: 7698018). Western analysis suggests that LGALS3BP is found in breast milk, semen, saliva, urine, and tears, in addition to serum (PMID: 8390986 ).

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