Anticorps Polyclonal de lapin anti-LGR4

LGR4 Polyclonal Antibody for IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 20150-1-PBS

Synonymes

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Galerie de données de validation

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  IHC staining of human small intestine using 20150-1-AP (same clone as 20150-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 20150-1-AP (LGR4 antibody) at dilution of 1:2000 (under 10x lens). This data was developed using the same antibody clone with 20150-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human small intestine using 20150-1-AP (same clone as 20150-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 20150-1-AP (LGR4 antibody) at dilution of 1:2000 (under 40x lens). This data was developed using the same antibody clone with 20150-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human small intestine using 20150-1-AP (same clone as 20150-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 20150-1-AP (LGR4 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 20150-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human small intestine using 20150-1-AP (same clone as 20150-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 20150-1-AP (LGR4 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 20150-1-PBS in a different storage buffer formulation.

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Informations sur le produit

20150-1-PBS cible LGR4 dans les applications de IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: LGR4 Protéine recombinante Ag13695
• Nom complet: leucine-rich repeat-containing G protein-coupled receptor 4
• Masse moléculaire calculée: 104 kDa
• Numéro d’acquisition GenBank: BC033039
• Symbole du gène: LGR4
• Identification du gène (NCBI): 55366
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

LGR4, also known as GPR48, is a membrane of the leucine-rich GPCR family. LGR4 is composed of a large NH2-terminal extracellular domain containing 18 LRRs, the seven membrane-spanning segments, and a COOH-terminal intracellular domain. LGR4 is a receptor for R-spondins that potentiates the canonical Wnt signaling pathway and is involved in the formation of various organs. It has also been shown that LGR4 regulates cyclic AMP/protein kinase A (PKA) signalling. (PMID: 23756652; 17178856; 24212090)

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