Anticorps Polyclonal de lapin anti-LGR5

LGR5 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 30007-1-PBS

Synonymes

FEX, GPR49, GPR67, G-protein coupled receptor 49, G-protein coupled receptor 67

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Galerie de données de validation

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  WB analysis using 30007-1-AP (same clone as 30007-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 30007-1-AP (LGR5 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30007-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 30007-1-AP (same clone as 30007-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 30007-1-AP (LGR5 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30007-1-PBS in a different storage buffer formulation.

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Informations sur le produit

30007-1-PBS cible LGR5 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: LGR5 Protéine recombinante Ag31625
• Nom complet: leucine-rich repeat-containing G protein-coupled receptor 5
• Masse moléculaire calculée: 907 aa, 100 kDa
• Poids moléculaire observé: 100 kDa
• Numéro d’acquisition GenBank: BC096324
• Symbole du gène: LGR5
• Identification du gène (NCBI): 8549
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Leucine-rich repeat-containing G-protein coupled receptor 5 (LGR5) also known as G-protein coupled receptor 49 (GPR49) or G-protein coupled receptor 67 (GPR67) is a protein that in humans is encoded by the LGR5 gene. It is a member of GPCR class A receptor proteins. R-spondin proteins are the biological ligands of LGR5. LGR5 is expressed across a diverse range of tissue such as in the muscle, placenta, spinal cord and brain and particularly as a biomarker of adult stem cells in certain tissues.LGR5 is crucial during embryogenesis as LGR null studies in mice incurred 100% neonatal mortality accompanied by several craniofacial distortions such as ankyloglossia and gastrointestinal dilation (PMID: 9642114, 16575208, 525477).

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