Anticorps Polyclonal de lapin anti-LILRA5/CD85f

LILRA5/CD85f Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 18821-1-PBS

Synonymes

LILRA5, CD85, CD85 antigen-like family member F, CD85f, ILT 11

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Galerie de données de validation

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  WB analysis of K-562 using 18821-1-AP (same clone as 18821-1-PBS)

  K-562 cells were subjected to SDS PAGE followed by western blot with 18821-1-AP (LILRA5 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18821-1-PBS in a different storage buffer formulation.

• 

  WB analysis of K-562 using 18821-1-AP (same clone as 18821-1-PBS)

  K-562 cells were subjected to SDS PAGE followed by western blot with 18821-1-AP (LILRA5 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18821-1-PBS in a different storage buffer formulation.

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Informations sur le produit

18821-1-PBS cible LILRA5/CD85f dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
• Masse moléculaire calculée: 299 aa, 33 kDa
• Poids moléculaire observé: 31-33 kDa
• Numéro d’acquisition GenBank: BC153203
• Symbole du gène: LILRA5
• Identification du gène (NCBI): 353514
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

LILRA5, also named as CD85f, ILT11, LILRB7 or LIR9, is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is a group of immune inhibitory and stimulatory receptors (PMID: 15304001). There are two membrane-bound and two soluble forms of LILRA5. The transmembrane LILRA5 contains a short cytoplasmic domain and a charged arginine residue within the transmembrane region (PMID: 19009525). It is mostly expressed in myeloid cells, including monocytes and neutrophils (PMID: 12393390). LILRA5 may play a role in triggering innate immune responses. It does not function in class I MHC antigens recognition (PMID: 16675463). The antibody recognizes the isoform 1 and isoform 2 of LILRA5.

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