Anticorps Recombinant de lapin anti-LINGO1

LINGO1 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241599A9

N° de cat : 84375-3-PBS

Synonymes

Leucine-rich repeat neuronal protein 6A, Leucine-rich repeat neuronal protein 1, Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1, Leucine-rich repeat and immunoglobulin domain-containing protein 1, LERN1

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Galerie de données de validation

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  WB analysis using 84375-3-RR (same clone as 84375-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84375-3-RR (LINGO1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84375-3-PBS in a different storage buffer formulation.

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Informations sur le produit

84375-3-PBS cible LINGO1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: LINGO1 Protéine recombinante Ag13597
• Nom complet: leucine rich repeat and Ig domain containing 1
• Masse moléculaire calculée: 70 kDa
• Poids moléculaire observé: 83 kDa
• Numéro d’acquisition GenBank: BC011057
• Symbole du gène: LINGO1
• Identification du gène (NCBI): 84894
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

LINGO-1 is a transmembrane receptor that contains 12 leucine-rich repeats and an immunoglobulin domain. It is expressed primarily in the central nervous system. LINGO-1 binds Nogo-66 receptor (NgR) and p75 and that is a functional component of the NgR/p75 signaling complex (PMID: 14966521). This protein has a calculated molecular weight of 70 kDa and migrates at higher molecular weight due to glycosylation (PMID: 21872576; 25257685; 18326721).

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