Anticorps Polyclonal de lapin anti-LIV-1/ZIP6

• Phare
• Validé par KD/KO

LIV-1/ZIP6 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 14236-1-PBS

Synonymes

LIV 1, SLC39A6, ZIP6, Estrogen-regulated protein LIV-1, LIV1

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Galerie de données de validation

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  WB analysis of HeLa using 14236-1-AP (same clone as 14236-1-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 14236-1-AP (LIV-1/ZIP6 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14236-1-PBS in a different storage buffer formulation.

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  WB analysis using 14236-1-AP (same clone as 14236-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 14236-1-AP (LIV-1/ZIP6 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14236-1-PBS in a different storage buffer formulation.

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  WB analysis of HeLa using 14236-1-AP (same clone as 14236-1-PBS)

  WB result of LIV-1/ZIP6 antibody (14236-1-AP; 1:4000; incubated at room temperature for 1.5 hours) with sh-Control and sh-LIV-1/ZIP6 transfected HeLa cells. This data was developed using the same antibody clone with 14236-1-PBS in a different storage buffer formulation.

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  WB analysis of MCF-7 using 14236-1-AP (same clone as 14236-1-PBS)

  MCF-7 cells were subjected to SDS PAGE followed by western blot with 14236-1-AP (LIV-1/ZIP6 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14236-1-PBS in a different storage buffer formulation.

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  IHC staining of human pancreas cancer using 14236-1-AP (same clone as 14236-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 14236-1-AP (LIV-1/ZIP6 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14236-1-PBS in a different storage buffer formulation.

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  IHC staining of human pancreas cancer using 14236-1-AP (same clone as 14236-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 14236-1-AP (LIV-1/ZIP6 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14236-1-PBS in a different storage buffer formulation.

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Informations sur le produit

14236-1-PBS cible LIV-1/ZIP6 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: LIV-1/ZIP6 Protéine recombinante Ag5478
• Nom complet: solute carrier family 39 (zinc transporter), member 6
• Masse moléculaire calculée: 85 kDa
• Poids moléculaire observé: 85-100 kDa, 48 and 32 kDa
• Numéro d’acquisition GenBank: BC039498
• Symbole du gène: SLC39A6/ZIP6
• Identification du gène (NCBI): 25800
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The zinc transporter LIV-1 (also known as SLC39A6 or ZIP6) was originally identified as an estrogen-induced gene in breast cancer cells. Elevated LIV-1 expression is reportedly related to cancer progression in various types of cancer, including breast, prostate, pancreatic, cervical and liver cancers. While correlation of LIV-1 and prognosis may vary. LIV 1 has 3 isoforms with MW of 85-100 (glycosylation and phosphorylation), 48 and 32 kDa while migrates as different bands in different lysates in SDS-PAGE.

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