Anticorps Polyclonal de lapin anti-LMO1

LMO1 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 26932-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis of mouse brain using 26932-1-AP (same clone as 26932-1-PBS)

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 26932-1-AP (LMO1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 26932-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 26932-1-AP (same clone as 26932-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 26932-1-AP (LMO1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 26932-1-PBS in a different storage buffer formulation.

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Informations sur le produit

26932-1-PBS cible LMO1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: LMO1 Protéine recombinante Ag25607
• Nom complet: LIM domain only 1 (rhombotin 1)
• Masse moléculaire calculée: 18 kDa
• Poids moléculaire observé: 18 kDa
• Numéro d’acquisition GenBank: BC069793
• Symbole du gène: LMO1
• Identification du gène (NCBI): 4004
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

LOM1 (LIM Domain Only 1), as a Protein Coding gene, encodes a cysteine-rich, two LIM domain transcriptional regulator. It may be involved in gene regulation within neural lineage cells potentially by direct DNA binding or by binding to other transcription factors. A chromosomal aberration involving LMO1 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL)(Uniprot). Diseases associated with LMO1 include T-Cell Acute Lymphoblastic Leukemia and Neuroblastoma (PMID:31830377). The downstream of LMO1-regulatory cascade includes a tumor-promoting LIMS1/ILK pathway, which has a potential to be a novel therapeutic target(PMID: 29695398). The molecular weight of LMO1 is 18 kDa.

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