Anticorps Polyclonal de lapin anti-LNX1

LNX1 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 13124-1-PBS

Synonymes

---

Galerie de données de validation

• 

  WB analysis of mouse testis using 13124-1-AP (same clone as 13124-1-PBS)

  mouse testis tissue were subjected to SDS PAGE followed by western blot with 13124-1-AP (LNX1 antibody) at dilution of 1:70 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13124-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse kidney using 13124-1-AP (same clone as 13124-1-PBS)

  mouse kidney tissue were subjected to SDS PAGE followed by western blot with 13124-1-AP (LNX1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13124-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

13124-1-PBS cible LNX1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: LNX1 Protéine recombinante Ag3823
• Nom complet: ligand of numb-protein X 1
• Masse moléculaire calculée: 728 aa, 81 kDa
• Poids moléculaire observé: 70 kDa
• Numéro d’acquisition GenBank: BC022983
• Symbole du gène: LNX1
• Identification du gène (NCBI): 84708
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

LNX1 (Ligand of Numb, protein X 1) was originally identified as a binding partner of the cell-fate determinant Numb and was reported to be involved in ubiquitylation and degradation of Numb. LNX1 contains four PDZ domains and may function as a scaffold for a multi-protein complex. LNX1 has two splicing variants, LNX1p70 and LNX1p80. LNX1p70 has the N-terminal Numb binding region and four PDZ domains, whereas LNX1p80 has an additional RING-finger domain at the N-terminus followed by a Numb-binding region and four PDZ domains. This antibody can detect both LNX1p70 and LNX1p80, around 70-80 kDa and 80-100 kDa, respectively.

{{ptg:RelatedPrimaryAntibodies}}