Anticorps Polyclonal de lapin anti-LPPR5

LPPR5 Polyclonal Antibody for IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 18842-1-PBS

Synonymes

PAP2D, Lipid phosphate phosphatase-related protein type 5, PAP2, Phosphatidic acid phosphatase type 2d, Phospholipid phosphatase-related protein type 5

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Galerie de données de validation

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  IHC staining of mouse brain using 18842-1-AP (same clone as 18842-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 18842-1-AP (LPPR5 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18842-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 18842-1-AP (same clone as 18842-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 18842-1-AP (LPPR5 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18842-1-PBS in a different storage buffer formulation.

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Informations sur le produit

18842-1-PBS cible LPPR5 dans les applications de IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: phosphatidic acid phosphatase type 2
• Masse moléculaire calculée: 35 kDa
• Numéro d’acquisition GenBank: NM_001010861
• Symbole du gène: PAP2D
• Identification du gène (NCBI): 163404
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The lipid phosphate phosphatase-related proteins (LPPRs), also known as plasticity-related genes (PRGs), are a family of six transmembrane proteins that are enriched in brain. To date, five members have been identified (LPPR1-LPPR5). LPPR5 is an integral membrane protein linked to neuronal plasticity, which impedes NogoA- and LPA-mediated RhoA kinase signaling. LPPR5 modulates the Rho-GTPase pathway involved in cancer growth, vascularization, and the adaptive response to changes in the microenvironment. LPPR5 is pivotal in influencing growth, angiogenesis, and therapeutic resistance. (PMID: 26183180, PMID: 35328529)

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