Anticorps Polyclonal de lapin anti-LRP2-Specific

• Phare
• Validé par KD/KO

LRP2-Specific Polyclonal Antibody for WB, IHC, IF-P, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, IF-P, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 19700-1-PBS

Synonymes

LRP2, LRP 2, Low-density lipoprotein receptor-related protein 2, gp330, Glycoprotein 330

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Galerie de données de validation

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  WB analysis using 19700-1-AP (same clone as 19700-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 19700-1-AP (LRP2-Specific antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 19700-1-PBS in a different storage buffer formulation.

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  IHC staining of human kidney using 19700-1-AP (same clone as 19700-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 19700-1-AP (LRP2-Specific antibody) at dilution of 1:8000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19700-1-PBS in a different storage buffer formulation.

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  IHC staining of human kidney using 19700-1-AP (same clone as 19700-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 19700-1-AP (LRP2-Specific antibody) at dilution of 1:8000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19700-1-PBS in a different storage buffer formulation.

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  IF Staining of human kidney using 19700-1-AP (same clone as 19700-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed human kidney tissue using LRP2-Specific antibody (19700-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 19700-1-PBS in a different storage buffer formulation.

• 

  IF Staining of human kidney using 19700-1-AP (same clone as 19700-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed human kidney tissue using LRP2-Specific antibody (19700-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 19700-1-PBS in a different storage buffer formulation.

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Informations sur le produit

19700-1-PBS cible LRP2-Specific dans les applications de WB, IHC, IF-P, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: low density lipoprotein-related protein 2
• Masse moléculaire calculée: 522 kDa
• Poids moléculaire observé: 522 kDa
• Numéro d’acquisition GenBank: NM_004525
• Symbole du gène: LRP2
• Identification du gène (NCBI): 4036
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

LRP2, also named as gp330 and Megalin, belongs to the LDLR family. It acts together with cubilin to mediate HDL endocytosis. LRP2 may participate in regulation of parathyroid hormone and para-thyroid-hormone-related protein release. Defects in LRP2 are the cause of Donnai-Barrow syndrome (DBS).

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