Anticorps Polyclonal de lapin anti-LRRC17

• Phare
• Validé par KD/KO

LRRC17 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 20918-1-PBS

Synonymes

UNQ3076/PRO9909, p37NB, Leucine-rich repeat-containing protein 17

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Galerie de données de validation

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  WB analysis of HeLa using 20918-1-AP (same clone as 20918-1-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 20918-1-AP (LRRC17 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20918-1-PBS in a different storage buffer formulation.

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  WB analysis using 20918-1-AP (same clone as 20918-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 20918-1-AP (LRRC17 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20918-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse heart using 20918-1-AP (same clone as 20918-1-PBS)

  mouse heart tissue were subjected to SDS PAGE followed by western blot with 20918-1-AP (LRRC17 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20918-1-PBS in a different storage buffer formulation.

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Informations sur le produit

20918-1-PBS cible LRRC17 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: LRRC17 Protéine recombinante Ag15117
• Nom complet: leucine rich repeat containing 17
• Masse moléculaire calculée: 441 aa, 52 kDa
• Poids moléculaire observé: 52 kDa
• Numéro d’acquisition GenBank: BC027903
• Symbole du gène: LRRC17
• Identification du gène (NCBI): 10234
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purifié par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Leucine-rich repeat-containing protein 17 (LRRC17) is an LRR protein predominantly expressed by osteoblasts. LRRC17 acts as a negative regulator of receptor activator of NF-kappaB ligand (RANKL)-induced osteoclast differentiation (PMID: 19336404). It has been reported that low plasma level of LRRC17 is an independent risk factor for osteoporotic fractures (PMID: 27355564).

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