Anticorps Polyclonal de lapin anti-LRRC2

LRRC2 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 28057-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 28057-1-AP (same clone as 28057-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 28057-1-AP (LRRC2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28057-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse skeletal muscle using 28057-1-AP (same clone as 28057-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue slide using 28057-1-AP (LRRC2 antibody) at dilution of 1:100 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28057-1-PBS in a different storage buffer formulation.

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Informations sur le produit

28057-1-PBS cible LRRC2 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons rat, souris

• Réactivité: rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: LRRC2 Protéine recombinante Ag27830
• Nom complet: leucine rich repeat containing 2
• Masse moléculaire calculée: 371 aa, 43 kDa
• Poids moléculaire observé: 38 kDa
• Numéro d’acquisition GenBank: BC029118
• Symbole du gène: LRRC2
• Identification du gène (NCBI): 79442
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Leucine Rich Repeat Containing 2 (LRRC2) was found to be localized to the mitochondria in human cells and transcriptionally regulated by the mitochondrial master regulator Pgc-1α. It has been reported that Lrrc2 transcript abundance correlates with that of β-MHC, a canonical marker of cardiac hypertrophy in humans, and experimentally demonstrated an elevation in Lrrc2 transcript in vitro and in vivo rodent models of cardiac hypertrophy as well as in patients with dilated cardiomyopathy. (PMID: 28158196)

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