Anticorps Polyclonal de lapin anti-LSM2

LSM2 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 10963-1-PBS

Synonymes

C6orf28, G7B, Protein G7b, snRNP, snRNP core Sm-like protein Sm-x5

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Galerie de données de validation

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  WB analysis using 10963-1-AP (same clone as 10963-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 10963-1-AP (LSM2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10963-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 10963-1-AP (same clone as 10963-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 10963-1-AP (LSM2 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10963-1-PBS in a different storage buffer formulation.

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Informations sur le produit

10963-1-PBS cible LSM2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: LSM2 Protéine recombinante Ag1412
• Nom complet: LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
• Masse moléculaire calculée: 11 kDa
• Poids moléculaire observé: 11 kDa
• Numéro d’acquisition GenBank: BC009192
• Symbole du gène: LSM2
• Identification du gène (NCBI): 57819
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family. Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing (PMID:15075370). Lsm2-Lsm8 (Lsm stands for Like Sm), binds and stabilizes the 3′ end of the spliceosomal U6 snRNA Lsm proteins facilitate the annealing of U6 snRNA with U4 snRNA in vitro and interact with the U4/U6 annealing factor Prp24, suggesting that Lsm proteins function in U4/U6 snRNP formation in vivo (PMID:15485930, 17251193).

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