Anticorps Monoclonal anti-Lactotransferrin/LTF

Lactotransferrin/LTF Monoclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

3D1G3

N° de cat : 68509-1-PBS

Synonymes

Lactoferrin, LTF, HLF2, Growth-inhibiting protein 12, GIG12

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Galerie de données de validation

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  WB analysis of human saliva using 68509-1-Ig (same clone as 68509-1-PBS)

  human saliva were subjected to SDS PAGE followed by western blot with 68509-1-Ig (Lactoferrin antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68509-1-PBS in a different storage buffer formulation.

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  IHC staining of human skin cancer using 68509-1-Ig (same clone as 68509-1-PBS)

  Immunohistochemical analysis of paraffin-embedded skin cancer slide using 68509-1-Ig (LTF antibody) at dilution of 1:4000 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68509-1-PBS in a different storage buffer formulation.

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Informations sur le produit

68509-1-PBS cible Lactotransferrin/LTF dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: Lactotransferrin/LTF Protéine recombinante Ag33645
• Nom complet: lactotransferrin
• Masse moléculaire calculée: 80 kDa
• Poids moléculaire observé: 78 kDa
• Numéro d’acquisition GenBank: BC015822
• Symbole du gène: LTF
• Identification du gène (NCBI): 4057
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

LTF(Lactotransferrin) is also named as GIG12, LF and belongs to the transferrin family. It is an iron binding transport protein which can bind two atoms of ferric iron in association with the binding of an anion, usually bicarbonate. LTF is also an important protein component of the innate immune system that is broadly distributed within the body fluids. It can contribute to the activation of both the innate and adaptive immune responses by promoting the recruitment of leukocytes and activation of dendritic cells(PMID:18453607). This protein has 2 isoforms produced by alternative promoter usage. The human LTF can be isolated two fragments, an N-terminal tryptic fragment having an MW of 30 kDa and a C-terminal tryptic fragment having an MW of 50 kDa by a mild tryptic digest(PMID:3790094).

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