Anticorps Polyclonal de lapin anti-LYRM5

LYRM5 Polyclonal Antibody for IF/ICC, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

IF/ICC, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 31548-1-PBS

Synonymes

ETFRF1

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Galerie de données de validation

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  IP experiment of mouse heart using 31548-1-AP (same clone as 31548-1-PBS)

  IP result of anti-LYRM5 (IP:31548-1-AP, 4ug; Detection:31548-1-AP 1:500) with mouse heart tissue lysate 1840 ug. This data was developed using the same antibody clone with 31548-1-PBS in a different storage buffer formulation.

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  IF Staining of A549 using 31548-1-AP (same clone as 31548-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed A549 cells using LYRM5 antibody (31548-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 31548-1-PBS in a different storage buffer formulation.

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Informations sur le produit

31548-1-PBS cible LYRM5 dans les applications de IF/ICC, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: LYRM5 Protéine recombinante Ag35889
• Nom complet: LYR motif containing 5
• Poids moléculaire observé: 11 kDa
• Numéro d’acquisition GenBank: BC071769
• Symbole du gène: LYRM5
• Identification du gène (NCBI): 144363
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

LYRM5, also known as ETFRF1, belongs to the Complex1_LYR-like Superfamily. LYRM5 is a mitochondrial protein and plays key roles in acetate metabolism, and in essential Fe-S cluster biogenesis. In vitro, LYRM5 was found to inhibit ETF by promoting the removal of flavin from the ETF holoenzyme, thus potentially regulating the rate of β-oxidation (PMID: 35402183, PMID: 36266680). The calculated molecular weight of LYRM5 is 11 kDa.

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