Anticorps Recombinant de lapin anti-Lactotransferrin/LTF

Lactotransferrin/LTF Recombinant Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, ELISA

Conjugaison

Non conjugué

CloneNo.

240280E2

N° de cat : 83409-5-PBS

Synonymes

Lactoferrin, LTF, HLF2, Growth-inhibiting protein 12, GIG12

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Galerie de données de validation

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  WB analysis of human saliva using 83409-5-RR (same clone as 83409-5-PBS)

  human saliva were subjected to SDS PAGE followed by western blot with 83409-5-RR (Lactotransferrin/LTF antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83409-5-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 83409-5-RR

  Biolayer interferometry (BLl) kinetic assays of 83409-5-RR against Human Lactotransferrin/LTF were performed. The affinity constant is 0.896 nM.

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Informations sur le produit

83409-5-PBS cible Lactotransferrin/LTF dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: lactotransferrin
• Masse moléculaire calculée: 78 kDa
• Poids moléculaire observé: 30 kDa, 51 kDa, 80 kDa
• Numéro d’acquisition GenBank: NM_002343.6
• Symbole du gène: LTF
• Identification du gène (NCBI): 4057
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

LTF(Lactotransferrin) is also named as GIG12, LF and belongs to the transferrin family. It is an iron binding transport protein which can bind two atoms of ferric iron in association with the binding of an anion, usually bicarbonate. LTF is also an important protein component of the innate immune system that is broadly distributed within the body fluids. It can contribute to the activation of both the innate and adaptive immune responses by promoting the recruitment of leukocytes and activation of dendritic cells(PMID:18453607). This protein has 2 isoforms produced by alternative promoter usage. The human LTF can be isolated two fragments, an N-terminal tryptic fragment having an MW of 30 kDa and a C-terminal tryptic fragment having an MW of 50 kDa by a mild tryptic digest(PMID:3790094).

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