Anticorps Polyclonal de lapin anti-Lipoprotein(a)

Lipoprotein(a) Polyclonal Antibody for IHC, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IHC, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 30675-1-PBS

Synonymes

LPA, Lp(a), LP, Apolipoprotein(a), APOA

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Galerie de données de validation

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  IHC staining of human placenta using 30675-1-AP (same clone as 30675-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 30675-1-AP (Lipoprotein(a) antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30675-1-PBS in a different storage buffer formulation.

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  IF Staining of HepG2 using 30675-1-AP (same clone as 30675-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using Lipoprotein(a) antibody (30675-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 30675-1-PBS in a different storage buffer formulation.

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Informations sur le produit

30675-1-PBS cible Lipoprotein(a) dans les applications de IHC, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Lipoprotein(a) Protéine recombinante Ag32907
• Nom complet: lipoprotein, Lp(a)
• Masse moléculaire calculée: 501 kDa
• Poids moléculaire observé: 501 kDa
• Numéro d’acquisition GenBank: NM_005577
• Symbole du gène: LPA
• Identification du gène (NCBI): 4018
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Lipoprotein(a), also known as Lp(a). The plasma concentration of human lipoprotein(a) is correlated with the risk of heart disease. A distinct feature of the Lp(a) particle is the apolipoprotein (a), which is associated with apoB-100, the main protein component of low-density lipoprotein. It is reported that apo(a), which has extensive homology to plasminogen, binds to immobilized fibronectin (PMID: 2531657). The binding of Lp(a) was localized to the C-terminal heparin-binding domain of fibronectin. It is enriched in liver tissue. The N-glycans are complex biantennary structures present in either a mono- or disialylated state.

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