Anticorps Recombinant de lapin anti-Ly-6C

Ly-6C Recombinant Antibody for FC

Hôte / Isotype

Rat / IgG2a

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

HK1.4

N° de cat : 65669-1-PBS

Synonymes

Ly6c, Ly 6C, Ly6c1

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Galerie de données de validation

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  FC experiment of mouse bone marrow cells using 65669-1-TR (same clone as 65669-1-PBS)

  1x10^6 mouse bone marrow cells were surface stained with 0.5 ug Anti-Mouse Ly-6C (HK1.4) Rat IgG2a RecAb (65669-1-TR, Clone: HK1.4) or Rat IgG2a Isotype Control Recombinant Antibody (98427-1-TR, Clone: 250862A1), and FITC anti-Rat IgG2a antibody. Cells were then stained with APC Anti-Mouse CD11b (M1/70) (APC-65055, Clone: M1/70). Cells were not fixed. This data was developed using the same antibody clone with 65669-1-PBS in a different storage buffer formulation.

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  FC experiment of mouse bone marrow cells using 65669-1-TR (same clone as 65669-1-PBS)

  1x10^6 mouse bone marrow cells were surface stained with 0.5 ug Anti-Mouse Ly-6C (HK1.4) Rat IgG2a RecAb (65669-1-TR, Clone: HK1.4) (red) or Rat IgG2a Isotype Control Recombinant Antibody (98427-1-TR, Clone: 250862A1) (blue), and FITC anti-Rat IgG2a antibody. Cells were not fixed. This data was developed using the same antibody clone with 65669-1-PBS in a different storage buffer formulation.

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Informations sur le produit

65669-1-PBS cible Ly-6C dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Rat / IgG2a
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: s/o
• Nom complet: lymphocyte antigen 6 complex, locus C1
• Numéro d’acquisition GenBank: BC010764
• Symbole du gène: Ly-6C
• Identification du gène (NCBI): 17067
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

Ly-6C (lymphocyte antigen 6 complex, locus C) is a 14-17 kDa GPI-linked cell surface antigen that belongs to the Ly-6 family of glycosyl phosphatidylinositol-anchored surface glycoproteins (PMID: 9192663). Ly-6C is expressed on mouse monocytes/macrophages, endothelial cells, granulocytes, thymocytes, and some T cell subsets (PMID: 2849552). The two alleles of Ly-6C, Ly-6C.1 and Ly-6C.2, result in differential expression of this protein on subpopulations of CD4+ T cells (PMID: 15057973; 9126982). Ly-6C has been reported as a marker of memory CD8+ T cells (PMID: 7543536).

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