Anticorps Monoclonal anti-Ly-6C

Ly-6C Monoclonal Antibody for FC

Hôte / Isotype

Rat / IgG2c

Réactivité testée

souris

Applications

FC

Conjugaison

CoraLite® Plus 488 Fluorescent Dye

CloneNo.

HK1.4

N° de cat : CL488-65296

Synonymes

AA682074, AA959465, Ly 6C, Ly6c, Ly6c1

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Galerie de données de validation

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  FC experiment of mouse bone marrow cells using CL488-65296

  1x10^6 mouse bone marrow cells were surface stained with 0.25 ug CoraLite® Plus 488 Anti-Mouse Ly-6C (HK1.4) (CL488-65296, Clone: HK1.4) (red), or 0.25 ug Isotype Control (blue). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: cellules médullaires de souris,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

CL488-65296 cible Ly-6C dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Rat / IgG2c
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: L3 cloned CTL cells
• Nom complet: lymphocyte antigen 6 complex, locus C1
• Numéro d’acquisition GenBank: BC010764
• Symbole du gène: Ly-6C
• Identification du gène (NCBI): 17067
• Conjugaison: CoraLite® Plus 488 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 493 nm / 522 nm
• Forme: Liquide
• Méthode de purification: Purification par affinité
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

Ly-6C (lymphocyte antigen 6 complex, locus C) is a 14-17 kDa GPI-linked cell surface antigen that belongs to the Ly-6 family of glycosyl phosphatidylinositol-anchored surface glycoproteins (PMID: 9192663). Ly-6C is expressed on mouse monocytes/macrophages, endothelial cells, granulocytes, thymocytes, and some T cell subsets (PMID: 2849552). The two alleles of Ly-6C, Ly-6C.1 and Ly-6C.2, result in differential expression of this protein on subpopulations of CD4+ T cells (PMID: 15057973; 9126982). Ly-6C has been reported as a marker of memory CD8+ T cells (PMID: 7543536).

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