Anticorps Recombinant de lapin anti-TAB2

TAB2 Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Cytometric bead array, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

230118G2

N° de cat : 82948-1-PBS

Synonymes

MAP3K7IP2, 230118G2, KIAA0733, Mitogen-activated protein kinase kinase kinase 7-interacting protein 2, TAB 2

---

Galerie de données de validation

• 

  WB analysis using 82948-1-RR (same clone as 82948-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 82948-1-RR (MAP3K7IP2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82948-1-PBS in a different storage buffer formulation.

• 

  Cytometric bead array standard curve of MP00082-3

  Cytometric bead array standard curve of MP00082-3, TAB2 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 82948-3-PBS. Detection antibody: 82948-1-PBS. Standard: Ag5742. Range: 0.625-20 ng/mL.

• 

  Affinity and Kinetic Characterization of 82948-1-RR

  Biolayer interferometry (BLl) kinetic assays of 82948-1-RR against Human TAB2 were performed. The affinity constant is 0.107 nM.

---

Informations sur le produit

82948-1-PBS cible TAB2 dans les applications de WB, Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: TAB2 Protéine recombinante Ag5742
• Nom complet: mitogen-activated protein kinase kinase kinase 7 interacting protein 2
• Masse moléculaire calculée: 76 kDa
• Poids moléculaire observé: 77 kDa
• Numéro d’acquisition GenBank: BC035910
• Symbole du gène: MAP3K7IP2
• Identification du gène (NCBI): 23118
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Tab2 has a role in the inflammatory signal transduction pathway and is involved in the reversal of NCoR-dependent and NFkB- or APP-mediated gene repression and androgen antagonist response. Besides, it is identified as a cofactor for ERBB4 to assemble NCoR corepressor complex in response to neuregulin [PMID:16469706]. It also functions as an adaptor that links TAK1 and TRAF6 in response to interleukin-1β (IL-1β) or tumour necrosis factor-α (TNF-α), and thereby mediates TAK1 activation [PMID:11460167].

{{ptg:RelatedPrimaryAntibodies}}