Anticorps Polyclonal de lapin anti-MARK4

• Phare
• Validé par KD/KO

MARK4 Polyclonal Antibody for IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 20174-1-PBS

Synonymes

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Galerie de données de validation

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  IHC staining of human kidney using 20174-1-AP (same clone as 20174-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney using 20174-1-AP (MARK4 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 20174-1-PBS in a different storage buffer formulation.

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  IHC staining of human kidney using 20174-1-AP (same clone as 20174-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney using 20174-1-AP (MARK4 antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 20174-1-PBS in a different storage buffer formulation.

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  IHC staining of human testis using 20174-1-AP (same clone as 20174-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human testis tissue slide using 20174-1-AP (MARK4 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 20174-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human testis using 20174-1-AP (same clone as 20174-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human testis tissue slide using 20174-1-AP (MARK4 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 20174-1-PBS in a different storage buffer formulation.

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  IHC staining of human gliomas using 20174-1-AP (same clone as 20174-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human gliomas slide using 20174-1-AP (MARK4 Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 20174-1-PBS in a different storage buffer formulation.

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  IHC staining of human gliomas using 20174-1-AP (same clone as 20174-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human gliomas slide using 20174-1-AP (MARK4 Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 20174-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human colon using 20174-1-AP (same clone as 20174-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon slide using 20174-1-AP (MARK4 Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 20174-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human colon using 20174-1-AP (same clone as 20174-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon slide using 20174-1-AP (MARK4 Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 20174-1-PBS in a different storage buffer formulation.

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Informations sur le produit

20174-1-PBS cible MARK4 dans les applications de IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: MARK4 Protéine recombinante Ag14013
• Nom complet: MAP/microtubule affinity-regulating kinase 4
• Masse moléculaire calculée: 752 aa, 83 kDa
• Numéro d’acquisition GenBank: BC009049
• Symbole du gène: MARK4
• Identification du gène (NCBI): 57787
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

MARK4(MAP/microtubule affinity-regulating kinase 4) is also named as KIAA1860, MARKL1 and belongs to the CAMK Ser/Thr protein kinase family and SNF1 subfamily. It is directly involved in microtubule organization in neuronal cells and may contribute to the pathological phosphorylation of tau in Alzheimer's disease and it also plays a role in hepatocellular carcinogenesis. This protein has 2 isoforms produced by alternative splicing with the molecular weight of 83 kDa and 75 kDa. MARK4 can exsit as 40-65 kDa forms in hippocampal homogenates from Alzheimer`s disease and non-demented elderly cases besides the full-length isoform 84 kDa. (PMID:24533944).

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