Anticorps Recombinant de lapin anti-MASP1

MASP1 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

251559F5

N° de cat : 86615-3-PBS

Synonymes

Complement factor MASP-3, Complement-activating component of Ra-reactive factor, Crarf, EC:3.4.21.-, Mannan-binding lectin serine protease 1

---

Galerie de données de validation

• 

  WB analysis of mouse serum using 86615-3-RR (same clone as 86615-3-PBS)

  mouse serum were subjected to SDS PAGE followed by western blot with 86615-3-RR (MASP1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86615-3-PBS in a different storage buffer formulation.

---

Informations sur le produit

86615-3-PBS cible MASP1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: MASP1 Protéine recombinante Eg4420
• Nom complet: mannan-binding lectin serine peptidase 1
• Masse moléculaire calculée: 80 kDa
• Poids moléculaire observé: 90 kDa
• Numéro d’acquisition GenBank: NM_008555.2
• Symbole du gène: Masp1
• Identification du gène (NCBI): 17174
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

MASP1, also known as CRARF, is a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties, which leads to activation of the associated proteases MASP1 and MASP2. The observed molecular weight of 90 kDa is consistent with the values described in the literature (PMID: 24472859, 12396007).

{{ptg:RelatedPrimaryAntibodies}}