Anticorps Polyclonal de lapin anti-MBD5

• Phare
• Validé par KD/KO

MBD5 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 15961-1-PBS

Synonymes

---

Galerie de données de validation

• 

  WB analysis of mouse heart using 15961-1-AP (same clone as 15961-1-PBS)

  mouse heart tissue were subjected to SDS PAGE followed by western blot with 15961-1-AP (MBD5 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15961-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human skeletal muscle using 15961-1-AP (same clone as 15961-1-PBS)

  human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 15961-1-AP (MBD5 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15961-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse skeletal muscle using 15961-1-AP (same clone as 15961-1-PBS)

  mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 15961-1-AP (MBD5 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15961-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

15961-1-PBS cible MBD5 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: MBD5 Protéine recombinante Ag8728
• Nom complet: methyl-CpG binding domain protein 5
• Masse moléculaire calculée: 292 aa, 31 kDa, 160 kDa
• Poids moléculaire observé: 160 kDa
• Numéro d’acquisition GenBank: BC014534
• Symbole du gène: MBD5
• Identification du gène (NCBI): 55777
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

In vertebrates, cytosine methylation in DNA is one of the major epigenetic modifications, which regulates many cellular events, including developmental gene expression, X chromosome inactivation, genome defense, and genomic imprinting. DNA methylation exerts regulatory functions by recruiting specific binding proteins that contain a highly conserved methyl-CpG binding domain (MBD) [PMID:12610534,16403636]. Methyl-CpG binding domain protein 5 (MBD5) belongs to the MBD family proteins, which play central roles in transcriptional regulation and development. It is a candidate gene involved in human 2q23.1 microdeletion syndrome [PMID:23077600].

{{ptg:RelatedPrimaryAntibodies}}