Anticorps Polyclonal de lapin anti-MCCC2

• Phare
• Validé par KD/KO

MCCC2 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 12117-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis of human liver using 12117-1-AP (same clone as 12117-1-PBS)

  human liver tissue were subjected to SDS PAGE followed by western blot with 12117-1-AP (MCCC2 antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12117-1-PBS in a different storage buffer formulation.

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  IP experiment of mouse kidney using 12117-1-AP (same clone as 12117-1-PBS)

  IP result of anti-MCCC2 (IP:12117-1-AP, 4ug; Detection:12117-1-AP 1:300) with mouse kidney tissue lysate 4000ug. This data was developed using the same antibody clone with 12117-1-PBS in a different storage buffer formulation.

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  IHC staining of human pancreas cancer using 12117-1-AP (same clone as 12117-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pancreas cancer using 12117-1-AP (MCCC2 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 12117-1-PBS in a different storage buffer formulation.

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Informations sur le produit

12117-1-PBS cible MCCC2 dans les applications de WB, IHC, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: MCCC2 Protéine recombinante Ag2767
• Nom complet: methylcrotonoyl-Coenzyme A carboxylase 2 (beta)
• Masse moléculaire calculée: 563 aa, 61 kDa
• Poids moléculaire observé: 61 kDa
• Numéro d’acquisition GenBank: BC014897
• Symbole du gène: MCCC2
• Identification du gène (NCBI): 64087
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

MCCC2(Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial) is also named as MCCB and belongs to the AccD/PCCB family. The putative 563-amino acid polypeptide has a calculated molecular mass of 61 kD and contains an N-terminal mitochondrial targeting sequence(PMID:11181649). It catalyzes carboxylation of 3 methylcrotonyl COA to form 3 methylglutaconyl-COA and is probably a dodecamer composed of six biotin-containing alpha subunits and six beta subunits. Defects in MCCC2 are the cause of methylcrotonoyl-CoA carboxylase 2 deficiency (MCC2D).

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