Anticorps Recombinant de lapin anti-MCOLN1

MCOLN1 Recombinant Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242586D4

N° de cat : 85339-1-PBS

Synonymes

242586D4, MG 2, ML1, ML4, MLIV

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Galerie de données de validation

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  WB analysis of rat kidney using 85339-1-RR (same clone as 85339-1-PBS)

  rat kidney tissue were subjected to SDS PAGE followed by western blot with 85339-1-RR (MCOLN1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85339-1-PBS in a different storage buffer formulation.

• 

  IHC staining of rat brain using 85339-1-RR (same clone as 85339-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 85339-1-RR (MCOLN1 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85339-1-PBS in a different storage buffer formulation.

• 

  IHC staining of rat brain using 85339-1-RR (same clone as 85339-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 85339-1-RR (MCOLN1 antibody) at dilution of 1:400 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85339-1-PBS in a different storage buffer formulation.

• 

  IHC staining of rat kidney using 85339-1-RR (same clone as 85339-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat kidney tissue slide using 85339-1-RR (MCOLN1 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85339-1-PBS in a different storage buffer formulation.

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Informations sur le produit

85339-1-PBS cible MCOLN1 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat

• Réactivité: Humain, rat
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: MCOLN1 Protéine recombinante Ag7493
• Nom complet: mucolipin 1
• Masse moléculaire calculée: 65 kDa
• Poids moléculaire observé: 60 kDa
• Numéro d’acquisition GenBank: BC005149
• Symbole du gène: MCOLN1
• Identification du gène (NCBI): 57192
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

MCOLN1, also named MLIV, ML4, MG-2, and Mucolipidin, belongs to the transient receptor (TC 1.A.4) family, Polycystin subfamily, and MCOLN1 sub-subfamily. It is playing a role in the endocytic pathway and in the control of membrane trafficking of proteins and lipids. MCOLN1 may play a major role in Ca2+ transport regulating lysosomal exocytosis. It is an autosomal recessive lysosomal storage disorder characterized by severe psychomotor retardation and ophthalmologic abnormalities, including corneal opacity, retinal degeneration, and strabismus.

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