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Anticorps Polyclonal de lapin anti-MCP-1/CCL2

MCP-1/CCL2 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 29547-1-PBS

Synonymes

CCL2, MCP1, MCP-1, chemokine (C C motif) ligand 2, CCL-2

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of THP-1 cells using MCP-1/CCL2 Polyclonal antibody (29547-1-AP)

    WB analysis of THP-1 using 29547-1-AP (same clone as 29547-1-PBS)

    Non-treated, and PMA, LPS and Brefeldin A treated THP-1 cells were subjected to SDS PAGE followed by western blot with 29547-1-AP (MCP1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29547-1-PBS in a different storage buffer formulation.

Informations sur le produit

29547-1-PBS cible MCP-1/CCL2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène Protéine recombinante
Nom complet chemokine (C-C motif) ligand 2
Masse moléculaire calculée 99 aa, 11 kDa
Poids moléculaire observé11 kDa
Numéro d’acquisition GenBankBC009716
Symbole du gène MCP-1/CCL2
Identification du gène (NCBI) 6347
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

MCP-1, ( also named as CCL2) is a member of the chemokine family. MCP-1 recruits monocytes, memory T cells, and dendritic cells to the sites of inflammation produced by either tissue injury or infection. MCP-1 has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Elevated expression of MCP-1 is associated with severe acute respiratory syndrome coronavirus 2 infection.

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