Anticorps Recombinant de lapin anti-MCP-1

MCP-1 Recombinant Antibody for ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

ELISA

Conjugaison

Non conjugué

CloneNo.

230270A7

N° de cat : 80847-2-RR

Synonymes

C C motif chemokine 2, CCL2, chemokine (C C motif) ligand 2, GDCF 2, HC11, HSMCR30, MCAF, MCP 1, MCP1, MCP-1, Monocyte chemotactic protein 1, Monocyte secretory protein JE, SCYA2, Small inducible cytokine A2, SMC CF

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Galerie de données de validation

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  Affinity and Kinetic Characterization of 80847-2-RR

  Biolayer interferometry (BLl) kinetic assays of 80847-2-RR against Human MCP-1 were performed. The affinity constant is 0.505 mM.

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Informations sur le produit

80847-2-RR cible MCP-1 dans les applications de ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: chemokine (C-C motif) ligand 2
• Masse moléculaire calculée: 99 aa, 11 kDa
• Numéro d’acquisition GenBank: BC009716
• Symbole du gène: MCP-1/CCL2
• Identification du gène (NCBI): 6347
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

Monocyte chemotactic protein 1 (MCP1; also known as CCL2), is a chemokine that can be expressed in monocytes, macrophages, and endothelial cells, and belongs to the CC subfamily of chemokines. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. Research has shown that the expression of MCP1 increases in the serum of patients with acute myocarditis. MCP1 is up-regulated in many types of CNS injury, including ischemia, hemorrhage, trauma, infection, hypoxia, and peripheral nerve axotomy. MCP1 has also been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, such as psoriasis, rheumatoid arthritis, and atherosclerosis.

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