Anticorps Recombinant de lapin anti-MDM1

MDM1 Recombinant Antibody for FC (Intra), Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC (Intra), Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

230425E2

N° de cat : 83141-5-PBS

Synonymes

Nuclear protein MDM1, 230425E2

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Galerie de données de validation

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  FC experiment of A431 using 83141-5-RR (same clone as 83141-5-PBS)

  1x10^6 A431 cells were intracellularly stained with 0.25 ug Mdm1 Recombinant Antibody (83141-5-RR, Clone:230425E2) and APC-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L)(red), or 0.25 ug Isotype Control (blue). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 83141-5-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 83141-5-RR

  Biolayer interferometry (BLl) kinetic assays of 83141-5-RR against Human MDM1 were performed. The affinity constant is 0.563 nM.

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Informations sur le produit

83141-5-PBS cible MDM1 dans les applications de FC (Intra), Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: MDM1 Protéine recombinante Ag10541
• Nom complet: Mdm1 nuclear protein homolog (mouse)
• Masse moléculaire calculée: 81 kDa
• Numéro d’acquisition GenBank: BC028355
• Symbole du gène: MDM1
• Identification du gène (NCBI): 56890
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Mdm1 is highly conserved in mammals as four sorting nexins (Snx): Snx13, 14, 19, and 25. Snx14 alleles are implicated in an autosomal-recessive neurological disease characterized by cellular vacuolization and granular plaque accumulation in late endosomes or autophagosomes. (PMID: 26283797)

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