Anticorps Polyclonal de lapin anti-MEF2A

MEF2A Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 28819-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 28819-1-AP (same clone as 28819-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 28819-1-AP (MEF2A antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28819-1-PBS in a different storage buffer formulation.

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  IHC staining of rat brain using 28819-1-AP (same clone as 28819-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 28819-1-AP (MEF2A antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28819-1-PBS in a different storage buffer formulation.

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  IHC staining of rat brain using 28819-1-AP (same clone as 28819-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 28819-1-AP (MEF2A antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28819-1-PBS in a different storage buffer formulation.

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Informations sur le produit

28819-1-PBS cible MEF2A dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: MEF2A Protéine recombinante Ag30349
• Nom complet: myocyte enhancer factor 2A
• Masse moléculaire calculée: 499 aa, 54 kDa
• Poids moléculaire observé: 50-70kDa
• Numéro d’acquisition GenBank: BC013437
• Symbole du gène: MEF2A
• Identification du gène (NCBI): 4205
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

MEF2A belongs to a family of DNA binding regulatory proteins. Each of these proteins which belong to the myocyte-specific enhancer factor-2 (MEF2) family binds to the MEF2 target DNA sequence present in the regulatory regions of many, if not all, muscle-specific genes. MEF2A plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. MEF2A also has key roles in cardiac and skeletal muscle development. MEF2A is especially abundant in granule neurons of the cerebellar cortex throughout the period of synaptogenesis. This antibody can detect two bands around 60 kDa to 70 kDa, the larger band may correspond to its post-translational modifications.(PMID: 15483225,16484498, 23486945 )

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