Anticorps Monoclonal anti-MEN1

MEN1 Monoclonal Antibody for WB, IHC, Cytometric bead array, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

WB, IHC, Cytometric bead array, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

3A6A11

N° de cat : 68473-1-PBS

Synonymes

3A6A11, MEAI, Menin, Menin 1, SCG2

---

Galerie de données de validation

• 

  WB analysis using 68473-1-Ig (same clone as 68473-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68473-1-Ig (MEN1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68473-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 68473-1-Ig (same clone as 68473-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 68473-1-Ig (MEN1 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68473-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 68473-1-Ig (same clone as 68473-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 68473-1-Ig (MEN1 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68473-1-PBS in a different storage buffer formulation.

• 

  Cytometric bead array standard curve of MP50886-1

  Cytometric bead array standard curve of MP50886-1, MEN1 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 68473-2-PBS. Detection antibody: 68473-1-PBS. Standard:Ag7566. Range: 1.563-200 ng/mL.

• 

  Cytometric bead array standard curve of MP50886-2

  Cytometric bead array standard curve of MP50886-2, MEN1 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 68473-1-PBS. Detection antibody: 68473-3-PBS. Standard:Ag7566. Range: 3.125-200 ng/mL.

---

Informations sur le produit

68473-1-PBS cible MEN1 dans les applications de WB, IHC, Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: MEN1 Protéine recombinante Ag7566
• Nom complet: multiple endocrine neoplasia I
• Masse moléculaire calculée: 68 kDa
• Poids moléculaire observé: 68-70 kDa
• Numéro d’acquisition GenBank: BC002544
• Symbole du gène: MEN1
• Identification du gène (NCBI): 4221
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

MEN1, also named as Menin or MEAI, is a tumor suppressor protein encoded by the MEN1 gene. It is located in nucleus and ubiquitous expression in spleen and lymph node. The calculated molecular weight of MEN1 is 68 kDa. Its inactivation has been implicated in tumors of many endocrine tissues. Germline inactivating mutations of MEN1 gene are the main cause of multiple endocrine neoplasia type 1 (MEN1), a syndrome characterized by tumors in the pituitary gland, the parathyroid glands, and the enteropancreatic neuroendocrine tissues. Recent study shows astroglia menin deficiency leads to depressive-like behaviors in mice.

{{ptg:RelatedPrimaryAntibodies}}