Anticorps Polyclonal de lapin anti-MEP1B

MEP1B Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 32828-1-PBS

Synonymes

EC:3.4.24.63, Endopeptidase-2, Meprin A subunit beta, Meprin B, N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta

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Galerie de données de validation

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  WB analysis using 32828-1-AP (same clone as 32828-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32828-1-AP (MEP1B antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32828-1-PBS in a different storage buffer formulation.

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Informations sur le produit

32828-1-PBS cible MEP1B dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: meprin A, beta
• Masse moléculaire calculée: 80 kDa
• Poids moléculaire observé: 100 kDa
• Numéro d’acquisition GenBank: NM_001308171.1
• Symbole du gène: MEP1B
• Identification du gène (NCBI): 4225
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

MEP1B, also known as meprin A subunit beta, is a gene that encodes a metalloprotease belonging to the Astacins family of zinc endopeptidases. The MEP1B gene is highly expressed in the small intestine and duodenum, and it is also expressed in the kidneys, leukocytes, and certain cancer cells. MEP1B encodes a metalloprotease that plays a key role in the hydrolysis of various substrates, including collagen, laminin, and elastin, which are major components of the extracellular matrix. This function is crucial for tissue development, repair, and remodeling.

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