Anticorps Polyclonal de lapin anti-METTL3

METTL3 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, singe, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 29314-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 29314-1-AP (same clone as 29314-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 29314-1-AP (METTL3 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29314-1-PBS in a different storage buffer formulation.

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  WB analysis using 29314-1-AP (same clone as 29314-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 29314-1-AP (METTL3 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29314-1-PBS in a different storage buffer formulation.

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  IHC staining of human lung cancer using 29314-1-AP (same clone as 29314-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 29314-1-AP (METTL3 antibody) at dilution of 1:800 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29314-1-PBS in a different storage buffer formulation.

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  IHC staining of human lung cancer using 29314-1-AP (same clone as 29314-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 29314-1-AP (METTL3 antibody) at dilution of 1:800 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29314-1-PBS in a different storage buffer formulation.

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  IHC staining of human stomach cancer using 29314-1-AP (same clone as 29314-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue slide using 29314-1-AP (METTL3 antibody) at dilution of 1:800 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29314-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human stomach cancer using 29314-1-AP (same clone as 29314-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue slide using 29314-1-AP (METTL3 antibody) at dilution of 1:800 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29314-1-PBS in a different storage buffer formulation.

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Informations sur le produit

29314-1-PBS cible METTL3 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, singe, souris

• Réactivité: Humain, rat, singe, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: METTL3 Protéine recombinante Ag30638
• Nom complet: methyltransferase like 3
• Masse moléculaire calculée: 64 kDa
• Poids moléculaire observé: 65-70 kDa
• Numéro d’acquisition GenBank: BC001650
• Symbole du gène: METTL3
• Identification du gène (NCBI): 56339
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

METTL3 is a key S-adenosyl-L-methionine-binding subunit, which is a component of a complex multicomponent enzyme that catalyzes the methylation of internal adenosine residues in eukaryotic mRNA, forming N6-methyladenosine. It contains 2 putative nuclear localization signals and 2 consensus methylation motifs. The calculated molecular weight of METTL3 is 64 kDa, but modified METTL3 is about 65-70 kDa.

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